Aitakin Ezzati (PhD student Sorbonne University)

Vision Institute
Aging in Vision and Action Lab
CNRS – INSERM – Sorbonne University
17, rue Moreau F-75012 Paris, France
Phone: +33 (0)1 53 46 26 52

email:

 

Research interests:  Visual Perception is an active process that is being curated and controlled by the statistics of the external stimuli as well as an active sampling of the visual field conducted by oculomotor behavior. During the aging process, the visual system is subjected to alteration at multiple levels, which inadvertently affects the perceptual process at every stage. How can the activity dynamics of the network (involved in the early visual stream) and information transfer (between visual stages) be controlled by external stimulation?
By focusing on the low-level changes at early stages of visual processing, understanding the underlying mechanisms of alterations as well as considering adaptability and plasticity of the system, I am striving to develop a neurocomputational framework that could link the low-level physiological/structural changes to the altered visual functions attributed to aging. It is particularly interesting to understand how retinal remodeling, changes in structure, and organization of the circuitry as well as the mosaic attributed to the size and shapes of receptive fields, is related to the oculomotor activity changes observed in psychophysical experiments. During my PhD I will be able to take advantage of the experimental data on retinal processing (adaptive optics imaging, retinal EEG) as well as psychophysical studies conducted by other lab members to design relevant testbeds/experiments to further develop the aforementioned computational framework that was instantiated by former members of the lab.

Short bio:  I have a background in physics, theoretical biophysics, and computational biology, which lead me to do my doctorate in computational neuroscience in the Action and Vision lab.

Keywords:  spiking neural models, visual processing, visual perception, visual aging, eye movements, retina, information processing.

CV and Publication List (pdf): [ download ]

Publications

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2017

  1. Matricon P, Ranganathan A, Warnick E, Gao Z-G, Rudling A, Lambertucci C, Marucci G, Ezzati A, Jaiteh M, Dal Ben D, Jacobson KA and Carlsson J (2017) Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A2Aadenosine receptor binding site. Scientific Reports, 7(1):6398.